Synthesis of some Novel Metal Complexes of 4-Hydroxy Benzopyran-2-Ones as Antimicrobial Agent

Complexes of 3-[{3-(3'-bromo phenyl)}-prop-2-enoyl]-4-hydroxy-6-methyl-2H-chromen-2-one with Cu(II), Ni(II), Fe(II), Co(II) and Mn(II) have been synthesized and characterized using elemental analysis, IR spectra and conductivity measurements. These studies revealed that they are having octahedral geometry of the type [ML2 (H2O)2]. In-vitro antimicrobial activity of all synthesized compounds and standard drugs have been evaluated against four strains of bacterial culture and one fungus, which includes two gram +ve bacterial culture and two gram -ve bacterial culture, which show net enhancement in activity on co-ordination of metals with ligand but moderate activity as compare to standard drugs.